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A Case Study on Functional Food Intake in a Diabetic Patient: No Such Thing as a Magic Bullet Part-II


FW FOONG, A.; SATO, K. A Case Study on Functional Food Intake in a Diabetic Patient: No Such Thing as a Magic Bullet Part-II JAS4QoL 2021, 7(1) 2 online at: https://as4qol.org/QLRiK

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A Case Study on Functional Food Intake in a Diabetic Patient: No Such Thing as a Magic Bullet Part-II

FOONG; Anthony FW SATO; Erina2  

R&D Department, Imex Japan Co Ltd, 22-8 Shimomidori-cho, Shinchiku, Kita-ku, Kyoto 603-8425, Japan (78imexfw@gmail.com

BACKGROUND: Useful ingredients in functional foods A and B previously improved certain physical symptoms (PSs) deficits due to ageing; however, blood sugar levels (monitored as glycemated hemoglobin or HbA1C) of a type-2 diabetic were unsatisfactory. We investigated the probable factors by focusing on the supply source, types and concentrates of sugar-regulating substances in ingredient mulberry leaf extract (MLE) as the extract was previously not well-defined. The revised functional food C (replaced previously known B), where all ingredients remained the same in quantity and supply sources, except MLE where the useful ingredient 1.2% 1-deoxynojirimycin (DNJ) was defined and obtained from a new supplier Z. METHODS: Volunteer patient P, who led a sedentary lifestyle, had continued intake of functional food A and complemented A with C after 2 control readings had been taken. Controls and blood analytical data were respectively monitored before and after combined A+C intake at 3-month (3-mo) intervals. Blood pressure (BP), body mass index (BMI), and other metabolic indexes were taken before (A alone) and after combined A+C intake. P led his usual normal life without dietary restrictions. PSs were also monitored before and after combined A+C intake. RESULTS: Blood pressure (BP) was normal, with slight improvement in BMI values. Total cholesterol (T-Cho), triglycerides (TG) levels varied in a similar pattern, which eventually registered normal after 9-mo combined A+C intake. HbA1c levels scored impressive improvements in a time-dependent manner: i.e. decreasing from 8.0 and 9 (controls) to 7.5, 6.9, and 6.8 at 3-, 6- and 9-mo combined A+C intakes, respectively. Improved PSs were well maintained. DISCUSSION: The BMI improved from overweight to normal status. Rebounds in T-Cho (3-, 6-mo) and TG (6-mo) levels were probably associated with high-calorie sweets taken in August. The most impressive finding in this study is the marked improvement in HbA1c findings. Replacement of MLE from a new source Z with defined 1-deoxynojirimycin (DNJ) concentrate made all the difference: the alpha-glucosidases-inhibiting DNJ, fagomine, and other active sugar-regulating components in MLE may have lowered blood sugar levels, thus improving HbA1c values. Functional foods comprising effective ingredients would most likely elicit useful effects, if the active ingredient with a defined concentrate was used.

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A Case Study on Functional Food Intake in a Diabetic Patient: No Such Thing as a Magic Bullet Part-I


FW FOONG, A.; HATTA, K. A Case Study on Functional Food Intake in a Diabetic Patient: No Such Thing as a Magic Bullet Part-I JAS4QoL 2020, 6(1) 3 online at: https://as4qol.org/TXZbX

Categories: > Full Papers, > Volume 6, Journal Articles, Volumes
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A Case Study on Functional Food Intake in a Diabetic Patient: No Such Thing as a Magic Bullet Part-I

FOONG; Anthony FW HATTA; Kanji

R&D Department, Imex Japan Co Ltd, 22-8 Shimomidori-cho, Shinchiku, Kita-ku, Kyoto 603-8425, Japan  (78imexfw@gmail.com

Department of Psychiatric Nursing, School of Nursing, Takarazuka University, 16-13-1, Shibata, Kita-ku, Osaka 530-0012, Japan

The present study reaffirmed that single-use of disorder-orientated functional foods may not be effective in resolving certain muscle- and orientation-relevant health problems. A male diabetic patient P on a functional food A (a product for blood pressure control) intake for more than 10 yr suffered from certain physical symptoms (PSs) such as forearm Grip-holding (FGH) muscular strength (PS-1), hindlimb joints (HJs) discomfort (PS-2), physical balance or orientation on one-legged standing (PS-3), and urination flow onset-latency and duration of complete emptying (PS-4) as well as poor metabolic indexes such as high levels of total cholesterols (T-Cho), low-density lipoprotein-cholesterols (LDL-C), triglycerides (TG), and HbA1C. When intake of A was complemented with daily product B, intake all PSs improved in a time-dependent manner; with different PS improvements requiring different intake duration: shorter intake duration for PS-1 (3-wk intake and thereafter), and longer intake durations for other PSs (at least more than 3-month intake). Additionally, high levels of T-Cho and relevant indexes were also improved over time with different intake durations, although the blood sugar levels (HbA1c) were unaffected. T-Cho (3-month intake), LDL-C (3-month intake), TG (after 6-month intake) were restored after different intake durations; however, blood sugar levels (HbA1c) were unaffected despite mulberry leaf extract having been documented to reduce blood sugar levels. Improvements of PSs and metabolic indexes were probably due to complementary effects of B whose effects in combination with A improved metabolic activity, nutritional, blood circulation and neurological effects and may have contributed to the favorable outcomes in this study. 

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