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Monthly Archives: April 2019

Regulation of Adiponectin Receptors Through PPAR-gamma Agonists in Systemic and Renal Hemodynamics in Diabetic Rats


Sattar, M. Z. A.; Afzal, S. Regulation of Adiponectin Receptors Through PPAR-gamma Agonists in Systemic and Renal Hemodynamics in Diabetic Rats JAS4QoL 2019, 5(1) 1 online at: https://as4qol.org/5U2Wj

Categories: > Volume 5, > Wisdom Notes, Journal Articles
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Munavvar Zubaid Abdul SATTAR*, Sheryar AFZAL

Department of Scientific Basis of Therapeutics, Faculty of Pharmacy, MAHSA University, Selangor, Malaysia (munavvar@mahsa.edu.my)

The adipose tissue as an object of study has dynamically entered the field of cardiology over the last decade. The communication between adipose tissue and other biological systems is accomplished through the expression of a large number of bioactive mediators, called adipokine or adipocytokines (Antoniades et al. 2009). The main adipocytokines are adiponectin (ADN), leptin, resistin, interleukin (IL-6), (Ryo et al. 2004), tumor necrosis factor-alpha (TNF-a) and the plasminogen activator-1 inhibitor (PAI-1). Adiponectin is distinguished by being not only the most abundant product of fat, but also for being one of the major involved in regulating various mechanisms in human body (Siasos, 2012). Adiponectin is a secreted protein consisting of 247 amino acids, produced exclusively by adipocytes. Adiponectin was independently identified by four laboratories; hence, the multiple names. Lodish laboratory first discovered adiponectin in 1995 as a protein named “Adipocyte Complement Related Protein of 30 kDa” (ACRP30) (Scherer et al. 1995).

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ICQoL2019 – International Conference on Quality of Life

The 2019 International Conference on Quality of Life was be held at Kyoto Pharmaceutical University from Sept 28-29, 2019. Further information can be found at the 2019 conference website.

Moving To Continuous Publication

Beginning January 2019 the editing committee has decided to adopt a continuous publishing model for Journal publication. Individual articles will be released online as they become ready, allowing a steady stream of informative quality articles. We will also be moving to a calendar year issue cycle. In traditional terms, each volume will encompass a single year and consist of a single issue. Publishing on a just-in-time basis allows authors to present their results in a timely fashion, and our readers, students, and colleagues to access our content and cite articles more quickly and free from the restrictions of a predefined timetable. As a result of these changes, the look and style, as well as the function, of the Journal will be different, and hopefully improved.

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